The Endocannabinoid System

The Endocannabinoid System

13th Jun 2022

All humans and animals have an Endocannabinoid System(ECS), our natural regulatory system. Composed of endocannabinoids, receptors, and enzymes, the ECS helps regulate our Nervous, Immune, and Endocrine System.

Endocannabinoids are cannabinoids produced by the body in order to self regulate as needed. Receptors, found all throughout the body, are spots that bind with endocannabinoids and either inhibit or activate signaling between that specific area and the brain. Enzymes are responsible for breaking down the endocannabinoids after they’ve completed their function.

This means that we carry receptors throughout our bodies that bind perfectly with cannabinoids produced by cannabis, which can be used to provide our regulatory system with additional help when needed to achieve balance.

Nervous System

The network of nerve cells which transmits nerve signals between parts of the body.

Immune

The network of cells and proteins that defends the body against infection.

Endocrine System

System of glands that produce hormones that regulate development, sleep, and mood.

Over the past decade scientists have seen connections between the Endocannabinoid system and a growing number of physiological functions including the nervous systems and minor organs. Further research indicated that the regulation of the Endocannabinoid system holds therapeutic promise for conditions including mood and anxiety disorders, movement disorders such as Parkinson’s and Huntington’s disease, neuropathic pain, multiple sclerosis, spinal cord injury, cancer, stroke, hypertension, glaucoma, obesity and metabolic syndromes, etc. [9]

Resources

[9]Pacher, Pál, et al. “The Endocannabinoid System as an Emerging Target of Pharmacotherapy.” Pharmacological Reviews, American Society for Pharmacology and Experimental Therapeutics, 1 Sept. 2006, http://pharmrev.aspetjournals.org/content/58/3/389.short 

[10]Alger, Bradley E. “Getting High on the Endocannabinoid System.” Cerebrum : the Dana Forum on Brain Science, The Dana Foundation, 1 Nov. 2013, http://www.ncbi.nlm.nih.gov/pmc/articles/PMC39972...

[11]Marzo, Vincenzo Di, and Fabiana Piscitelli. “The Endocannabinoid System and Its Modulation by Phytocannabinoids.” Neurotherapeutics, vol. 12, no. 4, 2015, pp. 692–698., doi:10.1007/s13311-015-0374-6, https://link.springer.com/article/10.1007/s13311-015-0374-6

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